• About
  • News
  • Projects
      Project 1 - Development of a Gene Therapy for Usher Syndrome Type 1B (USH1B)
        Project 2 - Evaluation of novel gene therapy approaches for USH2A
          Project 3 - Retina organoids as models for assessing pathomechanisms and effects of novel treatments inn retinal disorders
            Project 4 - Development of a one-time gene therapy for age-related macular degeneration
              Project 5 - Development of novel gene therapy strategies for treatment of autosomal dominant retinitis pigmentosa in a pig model
                Project 6 - Novel targets for gene therapy in diabetic retinopathy (DR)
                  Project 7 - RPE plasticity in the context of neurodegenerative disease: Understanding the limits, pushing the boundaries
                    Project 8 - Novel AI-based biomarkers for retinal gene therapy outcomes by integrating functional neuroimaging and retinal imaging
                      Project 9 - Integrating imaging, clinical and genetic data with machine learning to establish biomarkers for retinal diseases
                    • Project leaders
                    • Publications
                    1. DFG-Forschergruppe 5621
                    2. Prof. Dr. Nikolai Klymiuk

                    Prof. Dr. Nikolai Klymiuk

                    Project 5

                    Nikolai Klymiuk is Professor for Large Animal Models in Cardiovascular Research at the TU Munich. He is a leading expert in large (and in particular pig) animal models of human diseases. He has a strong track record in molecular genetics including gene editing technologies. Among others, he generated and characterized the first pig model of Usher syndrome type 1B, a severe human disease characterized by deafness and blindness.

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                    • News
                    • Projects
                      • Project 1 - Development of a Gene Therapy for Usher Syndrome Type 1B (USH1B)
                      • Project 2 - Evaluation of novel gene therapy approaches for USH2A
                      • Project 3 - Retina organoids as models for assessing pathomechanisms and effects of novel treatments inn retinal disorders
                      • Project 4 - Development of a one-time gene therapy for age-related macular degeneration
                      • Project 5 - Development of novel gene therapy strategies for treatment of autosomal dominant retinitis pigmentosa in a pig model
                      • Project 6 - Novel targets for gene therapy in diabetic retinopathy (DR)
                      • Project 7 - RPE plasticity in the context of neurodegenerative disease: Understanding the limits, pushing the boundaries
                      • Project 8 - Novel AI-based biomarkers for retinal gene therapy outcomes by integrating functional neuroimaging and retinal imaging
                      • Project 9 - Integrating imaging, clinical and genetic data with machine learning to establish biomarkers for retinal diseases
                    • Project leaders